Translations:Chondrogeneza/5/en

Chondrogenesis is the process of cartilage formation by multipotent stem cells of the third germ layer - the mesoderm. The stem cells at early stage of chondrogenic development, after receiving a differentiation signal, becomes a cartilage progenitor cell and loses the ability to differentiate into other cells of mesenchymal origin. Mesenchymal stem cells differentiate into cartilage progenitor cells, chondroblasts, which are characterized by the ability to create a functional extracellular matrix composed of collagen fibers, elastin, and proteoglycans. Chondrocytes formed after differentiation, together with the amorphous intercellular matrix, contribute to formation of various type of cartilage tissue . A characteristic feature of cartilage tissue is the lack of blood and lymph vessels, and the nourishment of chondrocytes occurs by diffusion from the perichondrium. There are no nerve endings in the cartilage tissue.