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# '''Embryonic Stem Cells (ESC)''' – derived from embryo cells (totipotent stem cells) or inner cell mass (pluripotent stem cells), they are able to differentiate into all type of cells of whole organism. However, the use of embryonic stem cells for therapeutic purpose arise ethical concerns, therefore their application should not be considered in regenerative medicine.<ref>Zakrzewski W, Dobrzyński M, Szymonowicz M, Rybak Z. Stem cells: past, present, and future. Stem Cell Res Ther. 2019 Feb 26;10(1):68. doi: 10.1186/s13287-019-1165-5.</ref>
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# '''Fetal and Perinatal Stem Cells''' – can be acquired from cord blood, cord tissue and postpartum placenta - their natural reservoir. In standard conditions the perinatal tissues are discarded  according to medical procedures.<ref>In 't Anker PS, Scherjon SA, Kleijburg-van der Keur C, de Groot-Swings GM, Claas FH, Fibbe WE, Kanhai HH. Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta. Stem Cells. 2004;22(7):1338-45. doi: 10.1634/stemcells.2004-0058.</ref> <ref>Miao Z, Jin J, Chen L, Zhu J, Huang W, Zhao J, Qian H, Zhang X. Isolation of mesenchymal stem cells from human placenta: comparison with human bone marrow mesenchymal stem cells. Cell Biol Int. 2006 Sep;30(9):681-7. doi: 10.1016/j.cellbi.2006.03.009. Epub 2006 Apr 22.</ref> <ref>Corrao S, La Rocca G, Lo Iacono M, Corsello T, Farina F, Anzalone R. Umbilical cord revisited: from Wharton's jelly myofibroblasts to mesenchymal stem cells. Histol Histopathol. 2013 Oct;28(10):1235-44. doi: 10.14670/HH-28.1235. Epub 2013 Apr 18.</ref> <ref>Kwon A, Kim Y, Kim M, Kim J, Choi H, Jekarl DW, Lee S, Kim JM, Shin JC, Park IY. Tissue-specific Differentiation Potency of Mesenchymal Stromal Cells from Perinatal Tissues. Sci Rep. 2016 Apr 5;6:23544. doi: 10.1038/srep23544.</ref>
# '''[[Somatyczne komórki macierzyste/en|Somatic Stem Cells]]'''– mature cells residing in the adult body and are responsible for tissues regeneration. These are multipotent stem cells (eg. hematopoietic cells) as well as unipotent cells (eg. satellite cells of skeletal muscle). The acquisition of [[somatyczne komórki macierzyste/en|somatic stem cells]] is well documented and many of them have found application in cellular therapies e.g. hematopoietic cell transplantation in the hematological disorders.<ref>Crisan M, Yap S, Casteilla L, Chen CW, Corselli M, Park TS, Andriolo G, Sun B, Zheng B, Zhang L, Norotte C, Teng PN, Traas J, Schugar R, Deasy BM, Badylak S, Buhring HJ, Giacobino JP, Lazzari L, Huard J, Péault B. A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell. 2008 Sep 11;3(3):301-13. doi: 10.1016/j.stem.2008.07.003.</ref> <ref>Murray IR, West CC, Hardy WR, James AW, Park TS, Nguyen A, Tawonsawatruk T, Lazzari L, Soo C, Péault B. Natural history of mesenchymal stem cells, from vessel walls to culture vessels. Cell Mol Life Sci. 2014 Apr;71(8):1353-74. doi: 10.1007/s00018-013-1462-6. Epub 2013 Oct 25.</ref> <ref>Elahi KC, Klein G, Avci-Adali M, Sievert KD, MacNeil S, Aicher WK. Human Mesenchymal Stromal Cells from Different Sources Diverge in Their Expression of Cell Surface Proteins and Display Distinct Differentiation Patterns. Stem Cells Int. 2016;2016:5646384. doi: 10.1155/2016/5646384. Epub 2015 Dec 6.</ref> <ref>Dumont NA, Rudnicki MA. Characterizing Satellite Cells and Myogenic Progenitors During Skeletal Muscle Regeneration. Methods Mol Biol. 2017;1560:179-188. doi: 10.1007/978-1-4939-6788-9_12.</ref> <ref>Klimczak A, Kozlowska U. Mesenchymal Stromal Cells and Tissue-Specific Progenitor Cells: Their Role in Tissue Homeostasis. Stem Cells Int. 2016;2016:4285215. doi: 10.1155/2016/4285215. Epub 2015 Dec 28.</ref> <ref>Kozlowska U, Krawczenko A, Futoma K, Jurek T, Rorat M, Patrzalek D, Klimczak A. Similarities and differences between mesenchymal stem/progenitor cells derived from various human tissues. World J Stem Cells. 2019 Jun 26;11(6):347-374. doi: 10.4252/wjsc.v11.i6.347.</ref>

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