Markery powierzchniowe/en - Historia wersji

Agnieszka Szyposzyńska o 11:49, 15 kwi 2021

2021-04-15T11:49:52Z

← poprzednia wersja		Wersja z 11:49, 15 kwi 2021
Linia 3:		Linia 3:


	Surface markers are specific proteins found on the surface of the cell which can be used for its identification. They can play different roles in the cell (e.g. function as either receptors or ligands); they are classified as markers based ~~purely~~ on their specificity for a particular type of cell.		Surface markers are specific proteins found on the surface of the cell which can be used for its identification. They can play different roles in the cell (e.g. function as either receptors or ligands); they are classified as markers exclusively based on their specificity for a particular type of cell.
	Cluster of differentiation (CD) is a system of surface molecule identification used for so-called immunophenotyping of the cells. For each type of cell, there is a specific combination of known CD antigens. For example, the markers specific to [[mezenchymalne komórki macierzyste/en\|mesenchymal stem cells]] (MSC) are CD73 (5’-nucleotidase), CD90 (Thy-1) and CD105 (endoglin); apart from that, they also typically express CD29 (integrin beta-1), CD44, and CD106 (VCAM-1) markers, and lack of CD34 and CD45, the markers specific for hematopoietic cells.<ref>Chan JK, Ng CS, Hui PK. A simple guide to the terminology and application of leucocyte monoclonal antibodies. Histopathology. 1988 May;12(5):461-80. doi: 10.1111/j.1365-2559.1988.tb01967.x </ref> <ref>Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015 Apr 28;35(2):e00191. doi: 10.1042/BSR20150025 </ref>		Cluster of differentiation (CD) is a system of surface molecule identification used for so-called immunophenotyping of the cells. For each type of cell, there is a specific combination of known CD antigens. For example, the markers specific to [[mezenchymalne komórki macierzyste/en\|mesenchymal stem cells]] (MSC) are CD73 (5’-nucleotidase), CD90 (Thy-1) and CD105 (endoglin); apart from that, they also typically express CD29 (integrin beta-1), CD44, and CD106 (VCAM-1) markers, and lack of CD34 and CD45, the markers specific for hematopoietic cells.<ref>Chan JK, Ng CS, Hui PK. A simple guide to the terminology and application of leucocyte monoclonal antibodies. Histopathology. 1988 May;12(5):461-80. doi: 10.1111/j.1365-2559.1988.tb01967.x </ref> <ref>Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015 Apr 28;35(2):e00191. doi: 10.1042/BSR20150025 </ref>

	=Bibliography=		=Bibliography=

Agnieszka Szyposzyńska o 14:58, 25 sty 2021

2021-01-25T14:58:39Z

← poprzednia wersja		Wersja z 14:58, 25 sty 2021
Linia 4:		Linia 4:

	Surface markers are specific proteins found on the surface of the cell which can be used for its identification. They can play different roles in the cell (e.g. function as either receptors or ligands); they are classified as markers based purely on their specificity for a particular type of cell.		Surface markers are specific proteins found on the surface of the cell which can be used for its identification. They can play different roles in the cell (e.g. function as either receptors or ligands); they are classified as markers based purely on their specificity for a particular type of cell.
	Cluster of differentiation (CD) is a system of surface molecule identification used for so-called immunophenotyping of the cells. For each type of cell, there is a specific combination of known CD antigens. For example, the markers specific to [[mezenchymalne komórki macierzyste/en\|mesenchymal stem cells]] (MSC) are CD73 (5’-nucleotidase), CD90 (Thy-1) and CD105 (endoglin); ~~except~~ from that, they also typically express CD29 (integrin beta-1), CD44, and CD106 (VCAM-1) markers, and lack of CD34 and CD45, the markers specific for hematopoietic cells.<ref>Chan JK, Ng CS, Hui PK. A simple guide to the terminology and application of leucocyte monoclonal antibodies. Histopathology. 1988 May;12(5):461-80. doi: 10.1111/j.1365-2559.1988.tb01967.x </ref> <ref>Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015 Apr 28;35(2):e00191. doi: 10.1042/BSR20150025 </ref>		Cluster of differentiation (CD) is a system of surface molecule identification used for so-called immunophenotyping of the cells. For each type of cell, there is a specific combination of known CD antigens. For example, the markers specific to [[mezenchymalne komórki macierzyste/en\|mesenchymal stem cells]] (MSC) are CD73 (5’-nucleotidase), CD90 (Thy-1) and CD105 (endoglin); apart from that, they also typically express CD29 (integrin beta-1), CD44, and CD106 (VCAM-1) markers, and lack of CD34 and CD45, the markers specific for hematopoietic cells.<ref>Chan JK, Ng CS, Hui PK. A simple guide to the terminology and application of leucocyte monoclonal antibodies. Histopathology. 1988 May;12(5):461-80. doi: 10.1111/j.1365-2559.1988.tb01967.x </ref> <ref>Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015 Apr 28;35(2):e00191. doi: 10.1042/BSR20150025 </ref>

	=Bibliography=		=Bibliography=

Agnieszka Szyposzyńska o 14:06, 19 sty 2021

2021-01-19T14:06:55Z

← poprzednia wersja		Wersja z 14:06, 19 sty 2021
Linia 3:		Linia 3:


	Surface markers are proteins found on the surface of the cell which can be used for its identification. They can play different roles in the cell (e.g. function as either receptors or ligands); they are classified as markers based purely on their specificity for a particular type of cell.		Surface markers are specific proteins found on the surface of the cell which can be used for its identification. They can play different roles in the cell (e.g. function as either receptors or ligands); they are classified as markers based purely on their specificity for a particular type of cell.
	Cluster of differentiation (CD) is a system of surface molecule identification used for so-called immunophenotyping of the cells. For each type of cell, there is a specific combination of known CD antigens. For example, the markers specific to [[mezenchymalne komórki macierzyste/en\|mesenchymal stem cells]] (MSC) are CD73 (5’-nucleotidase), CD90 (Thy-1) and CD105 (endoglin); except from that, they also typically express CD29 (integrin beta-1), CD44, and CD106 (VCAM-1) markers, and lack of CD34 and CD45, the markers specific for hematopoietic cells.<ref>Chan JK, Ng CS, Hui PK. A simple guide to the terminology and application of leucocyte monoclonal antibodies. Histopathology. 1988 May;12(5):461-80. doi: 10.1111/j.1365-2559.1988.tb01967.x </ref> <ref>Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015 Apr 28;35(2):e00191. doi: 10.1042/BSR20150025 </ref>		Cluster of differentiation (CD) is a system of surface molecule identification used for so-called immunophenotyping of the cells. For each type of cell, there is a specific combination of known CD antigens. For example, the markers specific to [[mezenchymalne komórki macierzyste/en\|mesenchymal stem cells]] (MSC) are CD73 (5’-nucleotidase), CD90 (Thy-1) and CD105 (endoglin); except from that, they also typically express CD29 (integrin beta-1), CD44, and CD106 (VCAM-1) markers, and lack of CD34 and CD45, the markers specific for hematopoietic cells.<ref>Chan JK, Ng CS, Hui PK. A simple guide to the terminology and application of leucocyte monoclonal antibodies. Histopathology. 1988 May;12(5):461-80. doi: 10.1111/j.1365-2559.1988.tb01967.x </ref> <ref>Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015 Apr 28;35(2):e00191. doi: 10.1042/BSR20150025 </ref>

	=Bibliography=		=Bibliography=

Agnieszka Szyposzyńska o 11:53, 20 paź 2020

2020-10-20T11:53:13Z

← poprzednia wersja		Wersja z 11:53, 20 paź 2020
Linia 4:		Linia 4:

	Surface markers are proteins found on the surface of the cell which can be used for its identification. They can play different roles in the cell (e.g. function as either receptors or ligands); they are classified as markers based purely on their specificity for a particular type of cell.		Surface markers are proteins found on the surface of the cell which can be used for its identification. They can play different roles in the cell (e.g. function as either receptors or ligands); they are classified as markers based purely on their specificity for a particular type of cell.
	Cluster of differentiation (CD) is a system of surface molecule identification used for so-called immunophenotyping of the cells. For each type of cell, there is a specific combination of known CD antigens. For example, the markers specific to [[~~mesenchymal stem cells~~\|mesenchymal stem cells]] (MSC) are CD73 (5’-nucleotidase), CD90 (Thy-1) and CD105 (endoglin); except from that, they also typically express CD29 (integrin beta-1), CD44, and CD106 (VCAM-1) markers, and lack of CD34 and CD45, the markers specific for hematopoietic cells.<ref>Chan JK, Ng CS, Hui PK. A simple guide to the terminology and application of leucocyte monoclonal antibodies. Histopathology. 1988 May;12(5):461-80. doi: 10.1111/j.1365-2559.1988.tb01967.x </ref> <ref>Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015 Apr 28;35(2):e00191. doi: 10.1042/BSR20150025 </ref>		Cluster of differentiation (CD) is a system of surface molecule identification used for so-called immunophenotyping of the cells. For each type of cell, there is a specific combination of known CD antigens. For example, the markers specific to [[mezenchymalne komórki macierzyste/en\|mesenchymal stem cells]] (MSC) are CD73 (5’-nucleotidase), CD90 (Thy-1) and CD105 (endoglin); except from that, they also typically express CD29 (integrin beta-1), CD44, and CD106 (VCAM-1) markers, and lack of CD34 and CD45, the markers specific for hematopoietic cells.<ref>Chan JK, Ng CS, Hui PK. A simple guide to the terminology and application of leucocyte monoclonal antibodies. Histopathology. 1988 May;12(5):461-80. doi: 10.1111/j.1365-2559.1988.tb01967.x </ref> <ref>Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015 Apr 28;35(2):e00191. doi: 10.1042/BSR20150025 </ref>

	=Bibliography=		=Bibliography=

Agnieszka Szyposzyńska: Utworzono nową stronę "=Bibliography="

2020-10-20T06:51:26Z

Utworzono nową stronę "=Bibliography="

← poprzednia wersja		Wersja z 06:51, 20 paź 2020
Linia 6:		Linia 6:
	Cluster of differentiation (CD) is a system of surface molecule identification used for so-called immunophenotyping of the cells. For each type of cell, there is a specific combination of known CD antigens. For example, the markers specific to [[mesenchymal stem cells\|mesenchymal stem cells]] (MSC) are CD73 (5’-nucleotidase), CD90 (Thy-1) and CD105 (endoglin); except from that, they also typically express CD29 (integrin beta-1), CD44, and CD106 (VCAM-1) markers, and lack of CD34 and CD45, the markers specific for hematopoietic cells.<ref>Chan JK, Ng CS, Hui PK. A simple guide to the terminology and application of leucocyte monoclonal antibodies. Histopathology. 1988 May;12(5):461-80. doi: 10.1111/j.1365-2559.1988.tb01967.x </ref> <ref>Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015 Apr 28;35(2):e00191. doi: 10.1042/BSR20150025 </ref>		Cluster of differentiation (CD) is a system of surface molecule identification used for so-called immunophenotyping of the cells. For each type of cell, there is a specific combination of known CD antigens. For example, the markers specific to [[mesenchymal stem cells\|mesenchymal stem cells]] (MSC) are CD73 (5’-nucleotidase), CD90 (Thy-1) and CD105 (endoglin); except from that, they also typically express CD29 (integrin beta-1), CD44, and CD106 (VCAM-1) markers, and lack of CD34 and CD45, the markers specific for hematopoietic cells.<ref>Chan JK, Ng CS, Hui PK. A simple guide to the terminology and application of leucocyte monoclonal antibodies. Histopathology. 1988 May;12(5):461-80. doi: 10.1111/j.1365-2559.1988.tb01967.x </ref> <ref>Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015 Apr 28;35(2):e00191. doi: 10.1042/BSR20150025 </ref>

	=~~Bibliografia~~=		=Bibliography=

Agnieszka Szyposzyńska: Utworzono nową stronę "Surface markers are proteins found on the surface of the cell which can be used for its identification. They can play different roles in the cell (e.g. function as eithe..."

2020-10-20T06:51:13Z

Utworzono nową stronę "Surface markers are proteins found on the surface of the cell which can be used for its identification. They can play different roles in the cell (e.g. function as eithe..."

← poprzednia wersja		Wersja z 06:51, 20 paź 2020
Linia 3:		Linia 3:


	~~Markery powierzchniowe to białka znajdujące się na powierzchni komórki, używane do jej identyfikacji~~. ~~Mogą one spełniać różne funkcje, np~~. ~~być receptorami lub aktywującymi receptory ligandami~~; ~~w ich klasyfikacji jako marker, istotna jest specyficzność dla danego typu komórek~~.System identyfikacji cząsteczek znajdujących się na powierzchni komórek w celu określenia ich tzw. immunofenotypu nazywany jest kompleksem zróżnicowania, lub antygenami różnicowania komórkowego (~~skr~~. CD, ~~od ang. Cluster~~ of ~~Differentiation). Dla każdego typu komórek właściwa jest obecność zdefiniowanego zestawu antygenów~~ CD. ~~Markerami CD specyficznymi dla~~ [[~~mezenchymalne komórki macierzyste~~ \|~~mezenchymalnych komórek macierzystych~~]] (MSC) ~~są:~~ CD73 (5’-~~nukleotydaza~~), CD90 (Thy-1) ~~oraz~~ CD105 (~~endoglina~~); ~~ponadto~~, ~~charakterystyczna dla tych komórek jest także ekspresja markerów~~ CD29 (~~integryna~~ beta-1), CD44, ~~czy~~ CD106 (VCAM-1) ~~oraz brak ekspresji markerów~~ CD34 ~~oraz~~ CD45, ~~specyficznych dla komórek hematopoetycznych~~. <ref>Chan JK, Ng CS, Hui PK. A simple guide to the terminology and application of leucocyte monoclonal antibodies. Histopathology. 1988 May;12(5):461-80. doi: 10.1111/j.1365-2559.1988.tb01967.x </ref> <ref>Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015 Apr 28;35(2):e00191. doi: 10.1042/BSR20150025 </ref>		Surface markers are proteins found on the surface of the cell which can be used for its identification. They can play different roles in the cell (e.g. function as either receptors or ligands); they are classified as markers based purely on their specificity for a particular type of cell.
			Cluster of differentiation (CD) is a system of surface molecule identification used for so-called immunophenotyping of the cells. For each type of cell, there is a specific combination of known CD antigens. For example, the markers specific to [[mesenchymal stem cells\|mesenchymal stem cells]] (MSC) are CD73 (5’-nucleotidase), CD90 (Thy-1) and CD105 (endoglin); except from that, they also typically express CD29 (integrin beta-1), CD44, and CD106 (VCAM-1) markers, and lack of CD34 and CD45, the markers specific for hematopoietic cells.<ref>Chan JK, Ng CS, Hui PK. A simple guide to the terminology and application of leucocyte monoclonal antibodies. Histopathology. 1988 May;12(5):461-80. doi: 10.1111/j.1365-2559.1988.tb01967.x </ref> <ref>Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015 Apr 28;35(2):e00191. doi: 10.1042/BSR20150025 </ref>

	=Bibliografia=		=Bibliografia=

Agnieszka Szyposzyńska o 06:48, 20 paź 2020

2020-10-20T06:48:58Z

← poprzednia wersja		Wersja z 06:48, 20 paź 2020
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	<languages/>		<languages/>
	Definition		=Definition=

Agnieszka Szyposzyńska: Utworzono nową stronę "Definition"

2020-10-20T06:48:50Z

Utworzono nową stronę "Definition"

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	<languages/>		<languages/>
	~~=Definicja=~~		Definition

Agnieszka Szyposzyńska: Utworzono nową stronę "Surface markers"

2020-10-20T06:48:40Z

Utworzono nową stronę "Surface markers"

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<languages/>
=Definicja=

Markery powierzchniowe to białka znajdujące się na powierzchni komórki, używane do jej identyfikacji. Mogą one spełniać różne funkcje, np. być receptorami lub aktywującymi receptory ligandami; w ich klasyfikacji jako marker, istotna jest specyficzność dla danego typu komórek.System identyfikacji cząsteczek znajdujących się na powierzchni komórek w celu określenia ich tzw. immunofenotypu nazywany jest kompleksem zróżnicowania, lub antygenami różnicowania komórkowego (skr. CD, od ang. Cluster of Differentiation). Dla każdego typu komórek właściwa jest obecność zdefiniowanego zestawu antygenów CD. Markerami CD specyficznymi dla [[mezenchymalne komórki macierzyste |mezenchymalnych komórek macierzystych]] (MSC) są: CD73 (5’-nukleotydaza), CD90 (Thy-1) oraz CD105 (endoglina); ponadto, charakterystyczna dla tych komórek jest także ekspresja markerów CD29 (integryna beta-1), CD44, czy CD106 (VCAM-1) oraz brak ekspresji markerów CD34 oraz CD45, specyficznych dla komórek hematopoetycznych. <ref>Chan JK, Ng CS, Hui PK. A simple guide to the terminology and application of leucocyte monoclonal antibodies. Histopathology. 1988 May;12(5):461-80. doi: 10.1111/j.1365-2559.1988.tb01967.x </ref> <ref>Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015 Apr 28;35(2):e00191. doi: 10.1042/BSR20150025 </ref>

=Bibliografia=